Angelman Syndrome Foundation Takes Steps to Strengthen the ASF International Clinic Network and Increase Access to Clinical Expertise Across Europe
New partnership established with Erasmus Angelman Clinic to improve care standards, treatment guidelines, and research participation for Angelman syndrome families in Europe.
Noblesville, In — The Angelman Syndrome Foundation (ASF) today announced the launch of the ASF International Clinic Network, a new initiative designed to expand access to expert clinical care and strengthen research readiness across Europe for individuals living with Angelman syndrome (AS). The initiative will be led in partnership with the Erasmus Angelman Clinic, part of the ENCORE Expertise Center for Angelman Syndrome in the Netherlands.
The ASF International Clinic Network builds upon ASF’s existing Clinic Network model in the United States, adding international alignment aimed at improving clinical pathways, establishing treatment guidelines, growing natural history data, and increasing access to clinical trials.
“Families across Europe deserve equitable access to expert, evidence-based care. This partnership allows us to build infrastructure that will improve care today, while ensuring clinical trial readiness for tomorrow,” said Amanda Moore, CEO of the Angelman Syndrome Foundation.
ASF International Clinic Network Goals
Through this partnership, ASF and Erasmus Angelman Clinic will work to:
- Ensure access to multidisciplinary expertise centers for all AS families in Europe.
- Develop and adopt standardized treatment guidelines tailored to individual country health systems.
- Expand natural history data collection in the LADDER format to enhance clinical understanding and research development.
- Identify and remove barriers to clinical trial participation.
- Increase education and knowledge sharing between clinical teams across Europe.
ASF has committed an initial four-year funding period, beginning October 1, 2025. The agreement includes annual progress reviews, financial reporting, and presentation of results at the ASF Research Symposium.
“Sharing data, harmonizing care, and removing barriers to clinical trials will change outcomes and quality of life for individuals with Angelman syndrome,” said Dr. Marie-Claire de Wit, Erasmus Angelman Clinic. “This collaboration brings a unified strategy to families and clinicians across Europe.”
The initiative is the first formal international expansion of the ASF International Clinic Network. ASF anticipates adding additional countries and partners in 2026 and beyond.
For more information about the Angelman Syndrome Foundation and the ASF International Clinic Network, visit: angelman.org/clinic
