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Ionis Shares Design of Champion Phase 3 Trial

September 9, 2026

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Ionis shared a letter to the Angelman syndrome community with an important update on the design of CHAMPION, their phase 3 clinical trial for ION582 (obudanersen) in people with Angelman syndrome due to UPD or ICD.

They are actively preparing to initiate the CHAMPION study.

Eligibility criteria are available on clinicaltrials.gov; additional details, including study locations, will be updated as they become available.