July 11, 2025
Oak Hill Bio announced the publication of rugonersen Phase 1 TANGELO study results in Nature Medicine.
The study provides evidence of improvement in brain activity and developmental ability in children with Angelman syndrome compared to natural history.
“These are promising results that mark a major milestone in the development of disease-modifying therapies for Angelman syndrome,” said Dr. Mark Shen, one of the principal investigators and authors of the paper.
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The mission of Angelman Syndrome Foundation is to advance the awareness and treatment of Angelman syndrome through education and information, research and support for individuals with Angelman syndrome, their families and other concerned parties. We exist to give all of them a reason to smile, with the ultimate goal of finding a cure.