The significance of EEG findings in Angelman Syndrome

$58,256

It is known that individuals with AS have an abnormal EEG during periods when seizures do not occur as well as when seizures do occur. Although the patterns of EEG abnormalities have been previously described in AS, there has been little work that correlates EEG patterns to the severity of epilepsy, or that compares individuals with AS who have different genetic mechanisms. This project analyzes many EEGs from individuals throughout the United States. This work builds upon previous experience this investigator has had in AS through involvement in a survey-based analysis of seizures among the Angelman community.